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诊断中耳肿瘤较困难,早期症状易与慢性化脓性中耳炎相混淆,可疑病例需综合检查方可确诊。血管性和颈静脉球体瘤活检有出血的危险,而无病检报告又不可能定性。借助核素检查可获得有关肿瘤病理特征的信息。本文旨在研究应用~(111)铟标记的抗癌抗生素博莱霉素进行诊断的可能性。检查了18例患者,其中13例中耳癌,5例为良性瘤(血管瘤2例,颈静脉球体瘤3例),另以10例乳腺肿瘤做对照。所注药物的活性为55.5～74最大生物量。~(111)铟博莱霉素具有γ射线,其量子能为171和245千电子伏,可用γ室或扫描器检测。鉴于~(111)铟的半衰期短(2.8天),药剂注射后头24小时排泄70～90%,故对患者的
Diagnosis of middle ear tumors is more difficult, and early symptoms are easily confused with chronic suppurative otitis media. Suspicious cases require comprehensive examination before they can be diagnosed. Vascular and jugular bulboma biopsy have the risk of bleeding, and no report of the disease can not be qualitative. With radionuclide examinations, information about the pathological features of the tumor can be obtained. This article aims to investigate the possibility of using the (111) indium-labeled anticancer antibiotic bleomycin for diagnosis. Eighteen patients were examined, including 13 with middle ear cancer, 5 with benign tumors (2 with hemangiomas, and 3 with jugular bulbous tumors), and 10 with breast tumors as controls. The activity of the injected drug was 55.5-74 maximal biomass. The ~(111) indole bleomycin has gamma rays, and its quantum energy is 171 and 245 kev, which can be detected by a gamma chamber or a scanner. In view of the short half-life of ~(111)indium (2.8 days), 70 to 90% of the first 24 hours after the injection of the drug is administered to the patient.