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目的:研究血清降钙素原(PCT)联合痰培养检测在呼吸道感染疾病中的应用价值。方法:选择2012年1月至2014年12月在我院接受治疗的呼吸道感染患者100例进行研究。分析痰培养菌群的分布情况以及PCT的检测结果,对比痰培养细菌感染者及真菌感染者的菌种分类及PCT检测结果。结果:检出病原菌的患者PCT水平均分别显著高于正常菌群及未见细菌生长的患者,差异均有统计学意义(均P<0.05)。细菌感染PCT阳性比例与真菌感染相比,差异无统计学意义(P>0.05)。细菌感染中,革兰氏阳性菌的PCT水平(0.74±0.33μg/L)与革兰氏阴性菌(0.72±0.24μg/L)对比,差异无统计学意义(P>0.05)。真菌感染中,白假丝酵母菌及烟曲霉菌的PCT阳性比例最高,分别为60.00%及80.00%。结论:血清PCT与痰培养检测应用于评价有呼吸道感染的患者病情,具有一定的反馈意义,但无法确定患者的呼吸道感染究竟是细菌感染亦或是真菌感染。
Objective: To investigate the value of serum procalcitonin (PCT) combined with sputum culture in the detection of respiratory tract infections. Methods: A total of 100 patients with respiratory tract infection who were treated in our hospital from January 2012 to December 2014 were selected. Analysis of the distribution of sputum culture flora and PCT test results, compared sputum culture bacterial infections and fungal infections species classification and PCT test results. Results: The PCT levels in patients with pathogenic bacteria were significantly higher than those in normal flora and those without bacterial growth (all P <0.05). There was no significant difference in the positive rate of bacterial infection between PCT and fungal infection (P> 0.05). In bacterial infection, the gram-positive bacteria PCT level (0.74 ± 0.33μg / L) and Gram-negative bacteria (0.72 ± 0.24μg / L), the difference was not statistically significant (P> 0.05). Among fungal infections, the highest positive rates of PCT positive were Candida albicans and Aspergillus fumigatus, which were 60.00% and 80.00%, respectively. CONCLUSION: The serum PCT and sputum culture test can be used to evaluate the condition of patients with respiratory tract infection. However, it is not certain whether the patients’ respiratory tract infections are bacterial infections or fungal infections.