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目的探讨营养不良儿童血清锌、铜、钙元素的变化及临床意义。方法本院收治的96例营养不良儿童为观察组,并选取同期同年龄段的健康儿童作为对照组,对其进行血清锌、铜、钙的定量测定及对照分析,给予营养不良儿童饮食纠正、补充能量、蛋白质、锌、钙等治疗,观察治疗前后观察组儿童血清锌、铜、钙水平的变化。结果观察组儿童的血清锌、钙平均值明显低于对照组儿童,差异有统计学意义,P<0.05;观察组儿童的血清铜水平与对照组儿童相比,差异无统计学意义,P>0.05;不同类型营养不良儿童的血清锌、铜、钙含量的平均值经比较,差异无统计学意义,P>0.05;观察组儿童经治疗后,血清锌、钙水平明显升高,与治疗前比较差异有统计学意义,P<0.05。结论营养不良儿童的血清锌、钙水平存在异常,对血清锌、钙水平进行定量测定,可以帮助判断儿童营养不良的程度及治疗效果。
Objective To investigate the changes and clinical significance of serum zinc, copper and calcium in children with malnutrition. Methods A total of 96 malnutrition children admitted to our hospital were selected as the observation group. Healthy children of the same age in the same period were selected as the control group. Quantitative determination and comparison of serum zinc, copper and calcium were conducted. Supplementation of energy, protein, zinc, calcium and other treatment, observe the changes of serum zinc, copper and calcium in observation group before and after treatment. Results The serum zinc and calcium in observation group were significantly lower than those in control group, the difference was statistically significant (P <0.05). There was no significant difference in serum copper levels between observation group and control group (P> 0.05; The mean zinc, copper and calcium levels in children with different types of malnutrition had no statistical significance (P> 0.05). After treatment, the levels of serum zinc and calcium in the observation group were significantly higher than those before treatment The difference was statistically significant, P <0.05. Conclusions There is abnormal serum zinc and calcium levels in malnourished children. Quantitative determination of serum zinc and calcium levels can help determine the degree of malnutrition and the therapeutic effect in children.