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目的分析拉莫三嗪在癫痫治疗中的应用效果。方法搜集本院神经内科2014年2月~2015年2月诊治的47例癫痫患者,根据使用药物的不同分为两组,甲组采用拉莫三嗪药物,乙组采用丙戊酸钠药物,对比临床疗效。结果 (1)甲组患者的治疗总有效率96.0%(24/25)高于乙组81.8%(18/22),P<0.05;(2)甲组患者的癫痫放电减少好于乙组,P<0.05;(3)甲组不良反应的发生率8.0%(2/25)低于乙组22.7%,P<0.05。结论拉莫三嗪治疗癫痫的临床疗效显著,减少患者的发病次数,癫痫得到有效控制。
Objective To analyze the effect of lamotrigine in the treatment of epilepsy. Methods A total of 47 patients with epilepsy who were diagnosed and treated in our department of neurology from February 2014 to February 2015 were divided into two groups according to the drugs used. Group A received lamotrigine, group B received sodium valproate, Comparison of clinical efficacy. Results (1) The total effective rate of group A was 96.0% (24/25), which was higher than that of group B (81.8%, P <0.05). (2) The decrease of epileptic discharge in group A was better than that of group B, P <0.05; (3) The incidence of adverse reactions in group A was 8.0% (2/25) lower than that in group B (22.7%, P <0.05). Conclusion Lamotrigine treatment of epilepsy clinical efficacy was significantly reduced the incidence of patients with epilepsy was effectively controlled.