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内分泌代谢病的治疗学独具特点,临床用药较为复杂,即受内外环境、饮食、活动的影响,也受体内代谢、药物动力学、遗传特征、正副反馈和药物间相互作用的影响。如果临床医生掌握不当,会招致不良反应,甚至意外和严重后果。因此,有必要总结归纳本组病临床用药特点,以提高治疗水平。一、口服降糖药物 (一) 磺脲类药物 1.药物种类第一代药物有甲磺丁脲(D860)、氯磺丙脲、甲磺氮(艹卓)脲,乙酰磺环己脲;第二代药物有优降糖(Glipizide)、吡磺环己脲、甲磺冰片脲(糖克利)、甲磺咯脲(达美康)。
Endocrine and metabolic disease treatment unique, clinical medication is more complicated, that is affected by internal and external environment, diet, activity, but also by the body metabolism, pharmacokinetics, genetic characteristics, positive and negative feedback and drug interactions. If clinicians misconduct, will lead to adverse reactions, and even unexpected and serious consequences. Therefore, it is necessary to summarize the clinical characteristics of this group of patients to improve the treatment level. First, the oral hypoglycemic drugs (a) sulfonylureas 1. The first generation of drug drugs are metobutyl urea (D860), chlorpropamide, metsulfuron (艹 Zhuo) urea, aceto sulfonylurea; The second-generation drugs are Glipizide, glipizide, meprobamate (meclizine), mesyzalme (dimethomol).