重病患者往往有不同程度的意识障碍,卧床时间长,气道分泌物排出困难,痰不易排出等。由于病情需要,侵入性操作较多如口咽通气管、气管插管、气管切开等,以及ICU患者大部分应用激素、患者机体免疫功能下降等因素肺部感染发病率及病死率明显提高。且获得性感染的病原菌为多重耐药 Patients with serious diseases often have different degrees of disturbance of consciousness, bed time, discharge of airway secretions, sputum is not easy to discharge. As the disease needs, more invasive operations such as oropharyngeal airway, endotracheal intubation, tracheotomy, etc., and most of the ICU patients with hormones, decreased immune function in patients with pulmonary infection incidence and mortality significantly increased. The acquired pathogenic bacteria were multi-drug resistant