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目的:对,索美拉唑与奥美拉唑治疗胃溃疡的治疗效果进行对比分析,并展开深入探讨,为临床用药提供参考。方法:选取我院于2014年6月至2015年9月收治的60例胃溃疡患者,随机分为对照组和观察组各30例,两组患者均行常规治疗,对照组在常规治疗基础上联合奥美拉唑进行治疗,观察组在常规治疗基础上联合埃索美拉唑进行治疗,对比分析两组患者的溃疡治疗总有效率、Hp根除有效率、夜间酸突破发生率。结果:经过治疗与对比后发现,观察组的溃疡治疗总有效率、Hp根除有效率、夜间酸突破发生率明显高于对照组(P<0.05);经过治疗后,两组患者的溃疡症状均有明显好转。结论:埃索美拉唑治疗胃溃疡的临床效果明显优于奥美拉唑,且不良反应较少,有助于改善患者预后,值得我们在临床上大力推广。
OBJECTIVE: To compare and analyze the therapeutic effects of somalazole and omeprazole in the treatment of gastric ulcer, and to conduct in-depth discussion for clinical reference. Methods: Sixty patients with gastric ulcer admitted from June 2014 to September 2015 in our hospital were randomly divided into control group and observation group of 30 cases. Both groups were treated routinely. On the basis of routine treatment, Combined with omeprazole treatment, the observation group on the basis of conventional treatment with esomeprazole treatment, comparative analysis of the two groups of patients the total effective rate of ulcer treatment, Hp eradication efficiency, the incidence of acid breakthrough at night. Results: After treatment and comparison, the total effective rate of ulcer treatment, effective rate of Hp eradication and nighttime acid breakthrough in observation group were significantly higher than those in control group (P <0.05). After treatment, the ulcer symptoms in both groups were There is a clear improvement. Conclusion: The clinical efficacy of esomeprazole in the treatment of gastric ulcer was significantly better than omeprazole, with fewer adverse reactions, which can help to improve the prognosis of patients. It is worth our efforts in clinical practice.