对8种异喹啉生物碱的免疫活性进行评估。植物原材料为从保加利亚附近的黑海岸采集的罂粟科届植物Glaucium flavum的茎和叶,经风干后分别以乙醇、石油醚、氢氧化铵、氯仿等提取,并制备生物碱制品。用柱层析法分离得到海罂粟碱、白蓬草坡芬、异波尔定、脱氢海罂粟碱及氧化海罂粟碱。由海罂 The immunological activities of eight isoquinoline alkaloids were evaluated. The plant material is stems and leaves of Glaucium flavum, a plant belonging to the genus Papaveraceae collected from the Black Sea coast near Bulgaria. After being air-dried, it is extracted with ethanol, petroleum ether, ammonium hydroxide, chloroform and the like, and alkaloid preparations are prepared. The papaverine, stevioside, isoborcipine, dehydroheparin and oxidized papaverine were separated by column chromatography. By the sea poppies