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目的通过分析腔隙性脑梗死(lacunar infarction,LI)患者和对照组神经影像学和超声资料,探讨其脑血管病变特点,以尽早进行干预,预防再发或加重。方法腔隙性脑梗死组患者110例和对照组90例,对所有研究对象全部行颈部血管彩超,经颅多普勒检查。结果腔隙性脑梗死组与对照组比较,颈部血管彩超显示颈动脉狭窄、斑块发生率明显增高(P<0.05)。TCD显示腔隙性脑梗死组患者责任病灶侧大脑中动脉和基底动脉血流速度下降,脉冲指数增高(P<0.05),提示腔隙性脑梗死组患者颅内血管床阻力升高,血流供应减少。结论大部分腔隙性脑梗死患者已经发生了血流动力学参数和血管壁的改变。
Objective To analyze the characteristics of cerebrovascular diseases by analyzing the neuroimaging and ultrasound data of patients with lacunar infarction (LI) and control group, so as to make early intervention and prevent recurrence or exacerbation. Methods A total of 110 patients with lacunar infarction and 90 patients with control group were enrolled in this study. All patients underwent neck-to-hip ultrasound and transcranial Doppler examinations. Results In lacunar infarction group, carotid artery stenosis and plaque incidence were significantly increased in cervical vascular ultrasound compared with control group (P <0.05). TCD showed that the lacunar infarction patients responsible lesion side of the middle cerebral artery and basilar artery blood flow velocity decreased, pulse index increased (P <0.05), suggesting that patients with lacunar infarction increased intracranial vascular bed resistance, blood flow Reduced supply. Conclusions Hemodynamic parameters and vessel wall changes have occurred in most patients with lacunar infarction.