喹诺酮类药物口服吸收良好。口服Norfloxacin1～2小时后即出现峰浓度。血药和尿药浓度随给药剂量的增加而增高。单次口服200和400 mg后峰血药浓度各为0.8±0.2和1.6±0.6mg/L。如果本品和食物一起口服,峰浓度稍见推迟,血药浓度曲线下的总面积则无变化。本品多次给药无蓄积作用。每8小时口服200mg,连服7日,血药浓度在2天内达到稳态。无论剂量如何,给药后48小时内约有25～40％的药物以原形通过肾小管主动分泌经尿排出。单次给药 Quinolones orally absorbed well. Peak concentration of oral Norfloxacin after 1 to 2 hours. Blood and urine concentration increased with the dose increased. A single oral dose of 200 and 400 mg peak plasma concentrations were 0.8 ± 0.2 and 1.6 ± 0.6 mg / L, respectively. If this product and food together, the peak concentration slightly delayed, no change in the total area under the plasma concentration curve. This product is administered repeatedly without accumulation. Oral every 8 hours 200mg, and even served on the 7th, plasma concentration reached steady state in 2 days. Regardless of the dosage, about 25 to 40% of the drug within 48 hours after the administration is excreted through the urine in the form of the active secretion through the renal tubules. Single administration