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目的探讨思利巴治疗年长弱视儿童的疗效。方法２０例１０～１５岁弱视儿童，口服思利巴２５０ｍｇ，每日２次，连服３个月。于服药前、服药６周、３个月时检查视力，同步检测ＰＥＲＧ和ＰＶＥＰ。结果口服思利巴３个月后弱视眼视力改善，ＰＶＥＰ的Ｐ１００和Ｎ７５潜伏期缩短，Ｐ１００振幅提高，而弱视眼ＰＥＲＧ各参数无明显改变。结论结果提示思利巴对改善大龄弱视儿童视功能有一定积极作用。
Objective To investigate the efficacy of silibin in the treatment of children with amblyopia. Methods Twenty children with amblyopia (10-15 years old) were given 250 mg sirolib twice a day for 3 months. In medication, medication 6 weeks, 3 months when checking vision, simultaneous detection of P ER and P VEP. Results Three weeks after oral administration of sirolib, the visual acuity of the amblyopic eyes was improved. The P100 and N75 latency of PVEP shortened, and the amplitude of P100 increased. However, the parameters of PERG did not change significantly in amblyopic eyes. Conclusion The results suggest that Si Liba to improve the visual function of children with amblyopia has a positive effect.