原肌球蛋白(tropomyosin,TM)是肌肉收缩过程中重要的调节蛋白质,其同源异构体在分布上具有组织特异性。TM有望成为一种新的肿瘤标记物。本文对TM的结构及其在膀胱癌中的表达研究进展作一综述。 Tropomyosin (TM) is an important regulatory protein in the process of muscle contraction. Its isoforms are tissue-specific in distribution. TM is expected to become a new tumor marker. This review summarizes the research progress of TM and its expression in bladder cancer.