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目的:观察桥本甲状腺炎患者血浆雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)以及白细胞雌激素受体(ER)的改变并探讨其意义。方法:选取桥本甲状腺炎患者20例,年龄21～54(43±6)岁,均为女性;对照组为健康女性志愿者20例,年龄18～50(40±5)岁。外周血白细胞ER测定采用放射配体结合法。同时检测血浆E2、FSH、LH的水平。结果:桥本甲状腺炎患者白细胞的ER为
Objective: To observe the changes of plasma estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) and leukocyte estrogen receptor (ER) in patients with Hashimoto’s thyroiditis. METHODS: Twenty patients with Hashimoto’s thyroiditis were selected, aged from 21 to 54 years old (43 ± 6) years, all of whom were female. The control group consisted of 20 healthy female volunteers, aged 18 to 50 years (40 ± 5 years). Peripheral blood leucocyte ER assay using radioligand binding method. At the same time, the level of plasma E2, FSH and LH were detected. Results: Hashimoto’s thyroiditis in patients with leukocyte ER