近年研究表明,从大戟科数种植物中分离的二萜类化合物显示出较强的血管松弛活性。作者研究了该科大戟属植物 E.canarie-nsis 中4种成分对离体家兔基底动脉和颈动脉的作用。该植物胶汁90 g 溶于700 mL 热甲醇中,冷至室温,过滤,除去白色三萜类沉淀。滤液真空蒸干,得白色油状物,溶于少量甲醇,上反相硅胶柱。提取液再次蒸干,所得粉状物 Recent studies have shown that the diterpenoids isolated from the plants of the Euphorbiaceae show strong vasorelaxation activity. The authors studied the effects of four components of E.canarie-nsis in this family on isolated rabbit basilar and carotid arteries. The plant gum 90 g was dissolved in 700 mL hot methanol, cooled to room temperature and filtered to remove the white triterpenoid precipitate. The filtrate was evaporated to dryness in vacuo to give a white oil which was dissolved in a small amount of methanol and applied on a silica gel column. The extract is again evaporated and the resulting powder