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骨容量取决于骨形成和骨吸收的相对比率，某些生长因子通过刺激成骨细胞增殖及其活性增加骨形成。一些骨源性生长因子可从骨基质浸出液和骨细胞或骨器官培养基中分离获得。目前发现的有骨生长因子（ＳＧＦ）／胰岛素，胰岛素样生长因子──Ⅰ和Ⅱ（ＩＧＦ６—Ⅰ和ＩＧＦ—Ⅱ），β—转化生长因子（ＴＧＦ－β），酸性和碱性成纤维细胞生长因子（ａＦＧＦ和ｂＦＧＦ），血小板源性生长因子（ＰＤＧＦ）。骨形成蛋白（ＢＭＰ）和造血因子等。它们具有不同的生物活性。包括丝裂原活性，促进分化活性，趋化活性和溶骨活性等。现在已知，骨细胞产生的生长因子贮存于细胞处基质中，也可以由邻近成骨细胞分泌以满足急需。即自分泌和邻分泌作用。骨吸收时，贮存在骨基质中的生长因子即释放出来，可起到邻分泌作用。骨是生长因子的储存仓库，测定生长因子含量可作为局部骨形成的参照依据。
Bone capacity depends on the relative ratio of bone formation to bone resorption, and some growth factors increase bone formation by stimulating osteoblast proliferation and its activity. Some osteogenic growth factors can be isolated from bone matrix leachate and from bone or bone organ culture. Currently found are bone growth factor (SGF) / insulin, insulin-like growth factors──Ⅰ and Ⅱ (IGF6-Ⅰ and IGF-Ⅱ), β-transforming growth factor (TGF-β), acidic and basic fibroblasts Growth factors (aFGF and bFGF), platelet-derived growth factor (PDGF). Bone morphogenetic protein (BMP) and hematopoietic factors. They have different biological activities. Including mitogen activity, promote differentiation activity, chemotactic activity and osteolytic activity. It is now known that growth factors produced by osteocytes are stored in the matrix of the cells and can also be secreted by adjacent osteoblasts to meet urgent needs. Namely autocrine and oocrine role. During bone resorption, the growth factors stored in the bone matrix are released and can play a role of oocrine. Bone is a growth factor storage warehouse, determination of growth factor content can be used as a reference for the formation of local bone.