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目的:探讨血小板平均体积(MPV)与老年急性ST段抬高型心肌梗死(STEMI)患者住院期间并发心力衰竭(HF)的相关性。方法:收集我院收治的172例老年STEMI患者,按照住院期间是否发生HF分为HF组(n=55例)和非HF组(n=117例),以患者MPV四分位分四组,比较以上各组之间相关指标的差异,用Logistic回归方程分析MVP与患者HF发生的关系。结果:HF组与非HF组在吸烟、发病至入院时间、前壁梗死、血清B型脑钠肽(BNP)、肌钙蛋白I(c Tn I)、左室射血分数(LVEF)、MVP存在统计学差异(P<0.05),HF组MVP水平高于非HF组(P<0.05);MVP四分位分组之间的心功能指标LVEF和血清BNP、HF发生率存在统计学差异(P<0.05),MVP的第四四分位组(Q4组)的HF发生率高于第一分位组及第二四分位组(Q1及Q2组);多因素Logistic回归方程分析显示高水平MPV是老年STEMI患者近期发生心力衰竭的独立危险因素(P<0.05);MVP四分位分组中,从Q1组到Q4组发生HF的风险值(OR)依次增高,且Q3及Q4组的OR值具有统计学意义(P<0.05)。结论:高水平MPV与老年STEMI患者住院期间HF发生密切相关,可能是其发生的独立危险因素,应当引起临床关注。
Objective: To investigate the correlation between platelet mean volume (MPV) and hospitalized patients with acute ST-segment elevation myocardial infarction (STEMI) complicated with heart failure (HF). Methods: A total of 172 elderly patients with STEMI admitted to our hospital were divided into four groups: HF group (n = 55) and non-HF group (n = 117) The differences between the above groups were compared, and the relationship between MVP and the occurrence of HF was analyzed by Logistic regression equation. Results: There were significant differences in smoking, morbidity and hospital admission time, anterior wall infarction, BNP, cTn I, LVEF, MVP (P <0.05). The MVP level in HF group was higher than that in non-HF group (P <0.05). There was a significant difference in the incidence of LVEF and BNP and HF between the two groups <0.05). The incidence of HF in Q4 group in MVP group was higher than that in the first and second quartiles (Q1 and Q2 group). Multivariate Logistic regression analysis showed that high level MPV was an independent risk factor for heart failure in elderly STEMI patients (P <0.05). In the MVP quartile group, the OR of HF patients increased from Q1 to Q4, and OR of Q3 and Q4 patients Values were statistically significant (P <0.05). Conclusion: High-level MPV is closely related to HF during hospitalization in elderly patients with STEMI, which may be an independent risk factor for its occurrence. It should be of clinical concern.