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作者对Ⅰ组8例过度肥胖病人(MO)在减肥前及胃成形术减肥后3月和一年,分别作了胰岛素和C肽动力学研究,并与6例年龄相同的非肥胖的正常人进行了对照。胰岛素动力学是通过分别代表胰岛素全身反应和胰岛素产量的胰岛素与C肽反应曲线下面积进行研究的。空腹对MO组血浆胰岛素C肽和葡萄糖浓度明显高于对照组,胰岛素有过度反应。肥胖者减肥后两者均明显下降,减肥一年后并维持其体重胰岛素效应可达到正常。在用高血糖期
The author of eight patients with obesity in Group I (MO) before and after weight loss and gastric plasty 3 months and one year after weight loss were made insulin and C-peptide kinetics, and 6 cases of the same age non-obese normal A comparison was made. Insulin kinetics is studied by the area under the curve of insulin-C peptide response, representing insulin’s systemic response and insulin production, respectively. The fasting plasma insulin C-peptide and glucose concentrations in MO group were significantly higher than those in control group, insulin was overreacted. Both obese people lose weight after a significant decline in weight loss after a year and maintain their body weight insulin effect can reach normal. In high blood sugar period