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冠状动脉无复流可产生严重心肌缺血危及患者的生命,甚至发生心血管崩溃立即致死。同时,无复流不仅是发生于再灌注当时的急性事件,而且对患者预后也有明显影响,其住院病死率和心肌梗死发生率比未发生无复流的患者高5～10倍:恶性心律失常、心脏破裂、心源性猝死、早期心力衰竭以及恢复期心室扩大和重构发生率均明显增加。本文从以下几方面探讨冠状动脉无复流的临床研究进展。
Coronary no-reflow can produce serious myocardial ischemia endanger the lives of patients, and even immediate cardiovascular death occurs. At the same time, no-reflow is not only an acute event occurred at the time of reperfusion, but also has a significant effect on the prognosis of patients. The incidence of in-hospital mortality and myocardial infarction is 5 to 10 times higher than that of patients without no-reflow: Malignant arrhythmia , Heart rupture, sudden cardiac death, early heart failure, and recovery of ventricular enlargement and remodeling were significantly increased. This article from the following aspects of coronary artery no-reflow clinical research.