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目的:从超声角度探讨舌癌肿瘤厚度与颈部淋巴结转移的关系。方法:使用口腔内超声探头检查测量37例原发性舌癌患者的肿瘤厚度,同时检查其颈淋巴结情况,记录各区淋巴结的数量、大小及内部回声,观察淋巴结的血流信号并判断其性质。使用SAS6.1软件包对数据进行χ2检验、非参数检验和Logistic回归分析。结果:术前超声测量的肿瘤厚度与病理标本测量的肿瘤厚度作非参数Wilcox秩和检验(P=0.2013),2种方法所测量的肿瘤厚度的均数差异无统计学意义。将肿瘤厚度与颈淋巴结转移作非参数检验(Spearmanr=0.6824,P<0.01),超声测量的肿瘤厚度与颈淋巴结转移情况呈正相关,Logistic回归分析显示,随着厚度的增加,淋巴结转移的风险也增大。结论:应用超声正确检测舌癌的肿瘤厚度及颈部转移的淋巴结,可以在术前对舌癌的临床分期进行更好地评估,为手术医师制订方案提供确切的依据。
Objective: To investigate the relationship between the thickness of tongue cancer and the lymph node metastasis in cervical lymph nodes from the perspective of ultrasound. Methods: Thirty-seven patients with primary tongue cancer were examined for the thickness of the tumor using the intraoral ultrasound probe. The cervical lymph nodes were also examined. The number, size and internal echo of the lymph nodes in each area were recorded. The blood flow signals of the lymph nodes were observed and their characteristics were determined. Data were subjected to χ 2 test, nonparametric test and logistic regression analysis using SAS 6.1 software package. Results: The non-parametric Wilcox rank sum test (P = 0.2013) was used to measure the thickness of the tumor measured by the preoperative ultrasonography and the thickness of the tumor measured by the pathological specimen. There was no significant difference in mean tumor thickness measured by the two methods. The tumor thickness and cervical lymph node metastasis were nonparametric test (Spearmanr = 0.6824, P <0.01). The thickness of the tumor measured by ultrasound was positively correlated with the cervical lymph node metastasis. Logistic regression analysis showed that with the increase of the thickness, the risk of lymph node metastasis Increase. Conclusion: Correct detection of tumor thickness and lymph node metastasis in tongue cancer with ultrasound can be used to evaluate the clinical stage of tongue cancer preoperatively, and provide exact evidence for the surgeon to make the plan.