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目的：寻找简便有效地高原失血性休克防治措施和救治方法。方法：在海拔４７００ｍ的昆仑山口泵站对氧合高渗高胶液复苏高原失血性休克家兔进行了高原现场观察。结果：氧合高渗高胶液能明显升高高原失血性休克动物的血压和心室内压以及心室内压的上升速度，加快舒张时心室内压的下降速度，提高休克动物的存活时间和存活率，明显改善休克动物的肺肾功能，而无其它任何不良反应，其作用明显优于等渗液体加维生素Ｃ和纳洛酮的作用。实验同时证明输入氧合高渗高胶液能明显降低休克动物的血浆ＥＴ水平，增高血浆ＮＯ水平，并维持肾内ＥＴ与ＮＯ的平衡，说明氧合液输入后能不同程度地影响血管内皮细胞及其它细胞对ＥＴ和ＮＯ的释放。结论：氧合高渗高胶液对高原失血性休克家兔有较好的复苏作用，其作用优于其它抗休克液
Objective: To find a simple and effective plateau hemorrhagic shock prevention and treatment measures and treatment methods. Methods: The altitude of 4700m altitude Kunlun Yamaguchi pumping station of oxygenated hypertonic hyperplastic fluid resuscitation high altitude hemorrhagic shock rabbits were observed on the plateau. Results: Oxygen-hypertonic hyperosmotic fluid could significantly increase the blood pressure and ventricular pressure and the rate of increase of ventricular pressure in hemorrhagic shock-induced plateau hemorrhagic shock, speed up the decline of ventricular pressure during diastole and increase the survival time and survival of shocked animals Rate, significantly improve the lungs and kidney function of shock animals, and no other adverse reactions, its role was significantly better than isotonic liquid plus vitamin C and naloxone role. The experiment also showed that the oxygenated hypertonic hyperosmotic solution can significantly reduce the level of ET in plasma, the level of plasma NO and the balance of ET and NO in the kidney, indicating that the oxygenated fluid can affect the vascular endothelial cells And other cells on ET and NO release. CONCLUSION: Oxygen-hypertonic hyperosmotic fluid has a better resuscitation effect on hemorrhagic shock rabbits at high altitude, and its effect is better than other anti-