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目的 :观察非溃疡性消化不良 (NU D)患儿服用吗丁啉治疗前后症状及体表胃电图改变 ,探讨吗丁啉对NUD的疗效。方法 :1998年 10月～ 1999年 10月在我院就诊的患儿 36例 ,均有消化道症状 ,且胃镜检查均无明显器质性病变 ,给予吗丁啉 0 .3m g/ kg,每日 3次口服治疗。用药前及用药 2周后观察临床症状及复查胃电图。结果 :服药 2周后患儿消化道症状以及体表胃电图变化明显改善 (均 P <0 .0 1)。结论 :吗丁啉可使胃电图恢复正常形态 ,频率增加 ,节律好转。胃电图检查安全可靠 ,简便易行 ,适合在小儿中应用
Objective: To observe the changes of symptoms and surface electrogastrogram of patients with non-ulcerative dyspepsia (NU D) before and after taking domperidone and to discuss the effect of domperidone on NUD. Methods: From October 1998 to October 1999, 36 children were treated in our hospital. All of them had gastrointestinal symptoms. Gastroscopy showed no obvious organic pathological changes. All patients were given morphine 0.3 mg / kg Day 3 oral treatment. Before treatment and 2 weeks after treatment to observe the clinical symptoms and review of the EGG. Results: The changes of gastrointestinal symptoms and body surface electrogastrogram in children after 2 weeks’ medication were significantly improved (all P <0.01). CONCLUSION: Dombutin can restore normal state of EGG, increase frequency and improve rhythm. Electrogastrogram is safe, easy to use, suitable for use in children