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目的:观察丹参川芎嗪注射液联合常规疗法治疗脑梗死的临床效果。方法:选取78例脑梗死患者,并按住院时间分为观察组与对照组各39例,2组患者入院后均给予常规治疗,观察组在常规治疗的基础上给予丹参川芎嗪注射液治疗,对照组给予依达拉奉注射液治疗,比较2组的临床治疗效果,观察治疗前后神经功能缺损评分(NIHSS)、日常生活活动能力(ADL)评分、血液流变学指标的变化情况。结果:治疗后,观察组总有效率为92.31%,对照组总有效率为74.36%,2组比较,差异有统计学意义(P<0.05)。2组NIHSS、ADL评分均较治疗前改善(P<0.05),观察组NIHSS低于对照组(P<0.05),ADL评分高于对照组(P<0.05)。2组血液流变学指标全血高切黏度、全血低切黏度、红细胞比容和纤维蛋白原较治疗前均有改善(P<0.05),观察组各项指标的改善情况均优于对照组(P<0.05)。结论:丹参川芎嗪注射液有助于神经功能的修复,提高患者的日常生活活动能力,改善血液流变状态,疗效优于依达拉奉注射液。
Objective: To observe the clinical effect of Salvia miltiorrhizae ligustrazine injection and conventional therapy in treating cerebral infarction. Methods: Seventy-eight patients with cerebral infarction were selected and divided into observation group and control group according to the length of stay in 39 cases. The two groups were given routine treatment after admission. The observation group was given Salviae Miltiorrhizae ligustrazine injection on the basis of routine treatment, The control group was treated with edaravone. The clinical effects of the two groups were compared. The changes of NIHSS, ADL and hemorheology indexes before and after treatment were observed. Results: After treatment, the total effective rate was 92.31% in the observation group and 74.36% in the control group. There was significant difference between the two groups (P <0.05). The scores of NIHSS and ADL were improved in both groups (P <0.05). The NIHSS in the observation group was lower than that in the control group (P <0.05), and the ADL score was higher than that in the control group (P <0.05). The indexes of hemorheology in the two groups were all higher than those before treatment (P <0.05), and the improvement of all indexes in the observation group was better than that of the control group Group (P <0.05). Conclusion: Salviae miltiorrhizae ligustrazine injection can promote the repair of nerve function, improve the activities of daily life of patients and improve the blood rheology. The curative effect is better than edaravone injection.