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目的 探讨乳腺癌保乳综合治疗的原则及近期疗效。方法 82例各期乳腺癌病例施保乳手术 (局部乳腺切除 +腋淋巴结清扫术 )、术中或术后瘤床插植近距放疗 +化疗。手术后 2~ 4周再接受全乳腺外照射剂量为 5 0Gy。激素受体阳性的病人均接受三苯氧胺治疗 ,随访时间中位数为 4 2个月。结果 82例全部存活 ,无一例出现局部复发。 1例出现骨转移。双乳对称 ,外形美观。其中 1例为双侧乳癌 ,两侧病理类型不同 ,均做保乳手术。结论 早期乳腺癌病人接受保乳综合治疗可以取得满意的临床效果 ,可成为早期乳腺癌的首选治疗方法。
Objective To explore the principle and short-term efficacy of comprehensive breast-conserving breast cancer treatment. Methods Eighty-two cases of breast cancer were treated with breast-conserving surgery (local mastectomy + axillary lymph node dissection), intraoperative or postoperative implantation of the tumor bed with brachytherapy + chemotherapy. Two to four weeks after surgery, the total dose of external mammography was 50 Gy. Patients with positive hormone receptors received tamoxifen for a median follow-up of 42 months. Results All 82 cases survived and no local recurrence occurred. One case had bone metastases. Double milk symmetry, beautiful appearance. One case was bilateral breast cancer, with different pathological types on both sides, all of which were breast-conserving surgery. Conclusion The comprehensive breast-conserving treatment for early-stage breast cancer patients can achieve satisfactory clinical results and can be the first choice for early breast cancer treatment.