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We experimentally demonstrate a quantum key distribution protocol using entangled photon pairs in orbital angular momentum (OAM).Here Alice uses a fixed phase hologram to modulate her OAM state on one photon with a spatial light modulator (SLM),while Bob uses the designed N different phase holograms for his N-based keys on the other photon with his SLM.With coincidences,Alice can fully retrieve the keys sent by Bob without reconciliation.We report the experiment results with N =3 and OAM eigenmodes |l =±t1>,and discuss the security from the light path and typical attacks.