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目的观察微波联合甘露聚糖肽治疗尖锐湿疣的疗效及尖锐湿疣的复发诱因。方法131例尖锐湿疣患者按随机和自愿原则分成2组,75例行微波治疗后肌注甘露聚糖肽(治疗组),另56例仅行微波治疗(对照组)。观察两组患者的复发率以及治疗组中达到医嘱要求者与未达到医嘱要求者的复发率。结果治疗组的复发率为30.67%,对照组的复发率为55.36%,治疗组明显优于对照组,两组比较有显著性差异(P<0.01)。治疗组中达到医嘱要求者复发率为12.20%,未达到医嘱要求组复发率为52.94%,两组复发率有显著性差异(P<0.01)。结论甘露聚糖肽能有效降低尖锐湿疣的复发率;术后嘱咐患者保护局部皮肤粘膜及避免免疫力下降的各种诱因,可降低尖锐湿疣的复发率。
Objective To observe the curative effect of microwave combined with mannan peptide on condyloma acuminatum and the inducement of recurrence of condyloma acuminatum. Methods A total of 131 patients with condyloma acuminatum were randomly divided into two groups according to the random and voluntary principles. 75 patients received intramuscular injection of mannan peptide (treated group) after microwave treatment, and the other 56 cases received microwave treatment only (control group). The recurrence rates of the two groups were observed, and the recurrence rates of the patients in the treatment group who reached the doctor’s orders and those who did not reach the doctor’s orders were observed. Results The recurrence rate was 30.67% in the treatment group and 55.36% in the control group, which was significantly better in the treatment group than in the control group. There was significant difference between the two groups (P <0.01). The recurrence rate was 12.20% in the treatment group and 52.94% in the group that did not meet the requirements of the doctor’s advice. There was significant difference between the two groups (P <0.01). Conclusion Mannan peptide can effectively reduce the recurrence rate of condyloma acuminatum. Postoperative patients were asked to protect the local skin and mucous membrane and avoid various causes of immunodeficiency, which can reduce the recurrence rate of condyloma acuminatum.