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目的探讨部分脾栓塞在肝癌介入治疗中的应用价值。方法在肝癌合并脾功能亢进介入治疗中,行肝动脉化疗栓塞的同时进行部分脾栓塞为治疗组,单纯肝动脉化疗栓塞治疗为对照组,2组各17例,观察肝脾同时栓塞组术后1周脾功能亢进改善情况,比较2组术后1周肝功能恢复情况、栓塞综合症持续时间和疼痛程度。结果肝、脾同时栓塞组脾功能亢进的情况得以改善,外周血WBC及PLT有不同程度升高,2组术后第7d肝功能损伤情况差别无统计学意义(P>0.05),但栓塞综合症持续时间较长(P<0.05),疼痛程度较重。结论对于肝癌合并脾功能亢进,在肝动脉化疗栓塞的同时进行部分脾栓塞治疗脾亢是一种安全、有效的方法。
Objective To investigate the value of partial splenic embolization in the interventional treatment of liver cancer. Methods In the interventional therapy of hepatocellular carcinoma with hypersplenism, partial splenic embolization was treated with transcatheter hepatic arterial chemoembolization as the treatment group, while hepatic arterial chemoembolization alone was used as the control group. Two groups of 17 cases each were treated with embolization of liver and spleen 1 week to improve the situation of hypersplenism, liver function recovery 1 week after surgery, embolism syndrome duration and pain level. Results The liver and spleen in the same embolization group improved the condition of hypersplenism, the level of WBC and PLT in peripheral blood increased to some extent. There was no significant difference in hepatic function between the two groups (P> 0.05) The duration of illness was longer (P <0.05) and the pain was heavier. Conclusion For hepatocellular carcinoma with hypersplenism, partial splenic embolization in the treatment of hypersplenism in the hepatic artery chemoembolization is a safe and effective method.