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目的：特比萘芬与咪康唑治疗皮肤真菌病的疗效比较。方法：患浅部真菌病病人１９０例，男性１０２例，女性８８例，年龄３８±ｓ１０ａ，随机分为特比萘芬组６０例，咪康唑组６０例，特比萘芬开放组７０例，特比萘芬组应用特比萘芬软膏外涂患部２次／ｄ，疗程１４ｄ；咪康唑组用咪康唑霜外涂２次／ｄ，疗程１４ｄ；在停药１４ｄ后观察疗效。结果：特比萘芬组与咪康唑组的疗效较治疗前皆十分显著（Ｐ＜０．０１）；真菌清除率特比萘芬组优于咪康唑组（Ｐ＜０．０１）。结论：特比萘芬治疗浅部真菌病疗效好、安全性高。
AIM: To compare the efficacy of terbinafine and miconazole in the treatment of dermatophytosis. Methods: 190 cases of superficial mycosis patients, 102 males and 88 females, age 38 ± s10a were randomly divided into terbinafine group 60 cases, miconazole group 60 cases, terbinafine open group 70 cases , Terbinafine group application of terbinafine ointment applied to the affected area 2 times / d, treatment 14d; miconazole group with miconazole cream 2 times / d, course of treatment 14d; observed after 14d withdrawal effect. Results: The effect of terbinafine group and miconazole group was significantly higher than that before treatment (P <0.01). The fungistasis rate of terbinafine group was better than that of miconazole group (P <0.01). Conclusion: Terbinafine is effective and safe for the treatment of superficial mycosis.