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目的比较强直性脊柱炎(AS)不同部位骨密度(BMD)测量精确性。方法对27例AS均行双能X线吸收法(DEXA)测定BMD,测定并记录腰椎、股骨颈和桡骨远端BMD Z值。记录患者病程,根据病程将患者分为A组(早期组,病程<10年)和B组(晚期组,病程≥10年)。结果 A、B组腰椎BMD Z值比较,差异有统计学意义(P<0.05),股骨颈与桡骨远端BMD Z值2组间比较,差异无统计学意义(P>0.05)。A组腰椎BMD更低,更能反映患者的低骨量状况;B组腰椎BMD增高,股骨颈BMD更能反映患者的低骨量状况。结论在早期AS患者中,腰椎BMD具有更好的精确性,更能准确反映其低骨量状态;但在晚期AS患者,腰椎BMD精确性降低,股骨颈BMD更能准确地反映其低骨量状态。
Objective To compare the measurement accuracy of bone mineral density (BMD) in different parts of ankylosing spondylitis (AS). Methods BMD was measured by DEXA in 27 AS patients, and the value of BMD of lumbar spine, femoral neck and distal radius was measured and recorded. The patient’s course of disease was recorded. According to the course of the disease, the patients were divided into group A (early stage, duration <10 years) and group B (late stage, duration ≥ 10 years). Results There was significant difference in Z value of lumbar BMD between group A and group B (P <0.05), but there was no significant difference between two groups (P> 0.05). The BMD of lumbar spine in group A was lower than that in group A, which could better reflect the low bone mass of patients. The BMD of lumbar spine of group B was higher than that of group B, and BMD of femoral neck better reflected the low bone mass of patients. Conclusion In early AS patients, BMD of lumbar spine is more accurate and more accurately reflect its low bone mass status. However, the accuracy of lumbar spine BMD is lower in patients with advanced AS, and the BMD of femoral neck can more accurately reflect the low bone mass status.