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绿脓杆菌(Pseudomoras aeruginosa)胞外粘质中的高分子多糖可作为免疫原用于小鼠烧伤后由假单胞菌引起的感染。高分子多糖可由培养物上清液或绿脓杆菌胞外粘质中分离,具有脂多糖O侧链的免疫型决定簇绿脓杆菌免疫1型(It-1)和免疫2型(It-2)的多糖是特性最明确的。在小鼠和兔中,It-1和It-2产生型特异性和交叉反应抗体。对两种多糖的抗体均有调理素作用。小鼠腹腔攻
Polysaccharide from Pseudomonas aeruginosa extracellular mucilage can be used as immunogen for infection caused by Pseudomonas in mice after burn. The macromolecular polysaccharides can be isolated from the culture supernatant or P. aeruginosa extracellular mucilage and have the immunotype Pseudomonas aeruginosa immunotype 1 (It-1) and the immunotype 2 (It-2 ) Of the polysaccharides is the most specific characteristics. It-1 and It-2 produce both type-specific and cross-reacting antibodies in mice and rabbits. The two polysaccharide antibodies have opsonization effect. Mouse abdominal attack