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轻链蛋白尿被认为是肾脏疾病和肾功衰竭的原因。1973年Graber等描述了发生在服用利福平的病人中的轻链蛋白尿,此后曾有人报告了2例肾功衰竭是由于利福平引起的轻链蛋白尿,作者报告了第三例。似乎有脱水现象时倾向于发生这种利福平
Light chain proteinuria is considered the cause of kidney disease and renal failure. Graber et al. Described the light chain proteinuria in patients taking rifampin in 1973, and since then two cases of renal failure have been reported due to rifampin-induced light chain proteinuria, the authors report the third. It seems that dehydration tends to occur when such rifampicin