对31例门脉高压症患者及30例正常人进行空腹血清胃泌素测定,结果:正常对照组(30例)血清胃泌素浓度54.13±20.60μg/L,肝硬化失代偿期(17例)为125.12±39.14μg/L,肝硬化失代偿期合并急性胃粘膜病变(14例)为185.52±45.43μg/L((?)±s)。此结果提示肝硬化门脉高压症病人常有高胃泌素血症。门脉高压者,胃粘膜糜烂出血与高胃泌素血症有密切相关。胃泌素是一种多肽,能扩张胃血管。血清胃泌素越高,并发上消化道出血的危害性越大, Fasting serum gastrin was measured in 31 patients with portal hypertension and 30 normal subjects. Serum gastrin levels were 54.13 ± 20.60μg / L in the control group (30 patients), 17 patients with decompensated cirrhosis Cases) were 125.12 ± 39.14μg / L, and the patients with decompensated liver cirrhosis with acute gastric mucosal lesions (185 cases) were 185.52 ± 45.43μg / L (± s ± s). This result suggests that patients with cirrhosis and portal hypertension often have hypergastrinemia. Portal hypertension, gastric mucosal erosion and bleeding are closely related to high blood gastrin. Gastrin is a polypeptide that dilates the blood vessels. Serum gastrin higher, the greater the danger of upper gastrointestinal bleeding,