论文部分内容阅读
目的探讨2型糖尿病患者餐后高血糖状态与并发症的关系。方法收集120例2型糖尿病患者的临床资料,包括年龄、性别、血压、体质量指数(BMI)、血脂、空腹血糖、三餐后2h血糖、糖基化血红蛋白(HbA1c)、眼底性状、尿微白蛋白、心彩超、颅脑CT、心电图等。并与60名健康体检者(对照组)进行比较。入选者均行颈部血管彩超检查测平均颈动脉内一中膜厚度(C-IMT)。结果(1)C-IMT值在2型糖尿病组明显高于对照组;有并发症组明显高于无并发症组。餐后2h血糖均值分布梯度与之一致。(2)相关性研究显示,C-IMT值与餐后2h血糖均值存在显著正相关,C-IMT及餐后2h血糖均值与糖尿病血管并发症发生率亦均呈显著正相关。结论餐后高血糖为2型糖尿病血管病变的独立危险因素。
Objective To investigate the relationship between postprandial hyperglycemia and complications in type 2 diabetic patients. Methods The clinical data of 120 type 2 diabetic patients were collected, including age, sex, blood pressure, body mass index (BMI), blood fat, fasting blood glucose, blood glucose at 2h after meals, HbA1c, Albumin, ultrasonography, brain CT, ECG and so on. And compared with 60 healthy people (control group). Participants underwent cervical vascular color Doppler ultrasound examination of the average carotid artery in a film thickness (C-IMT). Results (1) The C-IMT value in type 2 diabetes mellitus group was significantly higher than that in control group; the complication group was significantly higher than non-complication group. 2h postprandial blood glucose mean distribution gradient with the same. (2) Correlation study showed that there was a significant positive correlation between C-IMT value and 2-hour postprandial blood glucose, C-IMT and 2-hour postprandial blood glucose mean was significantly positively correlated with the incidence of diabetic vascular complications. Conclusion Postprandial hyperglycemia is an independent risk factor for type 2 diabetes mellitus.