论文部分内容阅读
本文报道了急性白血病儿童用大剂量化疗、超分次全身照射(TBI)作预处理。进行骨髓移植(BMT)治疗后性腺功能的回顾性分析结果。 方法 对象为1980年2月～1991年3月间进行BMT,并在BMT后常规检测了性腺功能的急性白血病儿童33例,男17例,女16例。急性淋巴细胞白血病20例,急性髓细胞白血病13例。确诊时中数年龄为4.6(0.4～11.2)岁,BMT时为7.1(3.7～11.6)岁。移植前均进行了化疗,23例(男10例、女13例)应用了烷
This article reports the use of high-dose chemotherapy and super-fractionated total body irradiation (TBI) in children with acute leukemia for pretreatment. Retrospective analysis of gonadal function after bone marrow transplantation (BMT) treatment. Methods The subjects were BMT between February 1980 and March 1991 and 33 children with acute leukemia with gonadal function routinely tested after BMT. There were 17 males and 16 females. 20 cases of acute lymphoblastic leukemia, acute myeloid leukemia in 13 cases. The median age at diagnosis was 4.6 (0.4 to 11.2) years and 7.1 (3.7 to 11.6) years at BMT. All patients underwent chemotherapy before transplantation, and 23 patients (10 males and 13 females) received alkane