吸烟的早期,常常造成小气道急性炎症反应,这种病理变化可导致小气道功能障碍。但这类吸烟者常常缺乏呼吸道症状,同时常规肺功能,如肺容量,用力呼气量等各项指标的测定,往往出现正常的结果。于60年代末至70年代早期,发展了许多能测定小气道功能试验,如 In the early stages of smoking, acute airway inflammation often results and this pathological change can lead to small airway dysfunction. However, these smokers often lack of respiratory symptoms, while conventional lung function, such as lung capacity, forced expiratory volume and other indicators of measurement, often appear normal results. From the late 1960s to the early 1970s, a number of tests have been developed that measure small airway function, such as