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[目的]探讨慢性肾病维持性血液透析患者家庭功能与抑郁情绪的相关性。[方法]采用一般情况调查问卷、家庭关怀指数问卷和贝克抑郁自评量表，对100例慢性肾病维持性血液透析患者调查研究，分析患者家庭功能与抑郁情绪的相关性。[结果]19例（19％）患者存在家庭功能障碍，62例（62％）的患者存在抑郁情绪；患者的家庭功能总分与各维度评分与抑郁情绪评分均呈负相关（ P ＜0．05）；回归分析显示，家庭功能障碍、疾病负担与疾病程度是患者抑郁情绪形成独立危险因素。[结论]提高家庭成员对慢性肾病维持性血液透析患者的关爱，可预防和减轻患者的抑郁情绪。“,”[Objective] To explore the relationship between family function and depression in maintenance he-modialysis patients with chronic kidney disease .[Methods] Totally 100 maintenance hemodialysis patients with chronic kidney disease were investigated by using demographic information questionnaire ,family APGAR and Beck depression inventory(BDI) .The relationship between family function and depression was analyzed .[Results] A-mong 100 patients ,19 patients(19% ) had family dysfunction ,and 62 patients(62% ) had depression .The total score and factors scores of family function were all negatively related to the score of depression ( P <0 .05) .Re-gression analysis showed that family dysfunction ,self-reported financial burden and disease activity were the inde-pendent risk factors of depression .[Conclusion] Improving the care and love of family members on maintenance hemodialysis patients with chronic kidney disease can prevent and relieve the depressive mood of patients .