【摘 要】
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BACKGROUND Percutaneous coronary intervention(PCI)in patients with unprotected left main coronary artery disease(UL-MCAD)is increasing strategy in coronary arte
【机 构】
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Department of Cardiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy
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BACKGROUND Percutaneous coronary intervention(PCI)in patients with unprotected left main coronary artery disease(UL-MCAD)is increasing strategy in coronary artery patients.However,there is a lack of knowledge on the impact of sex on out-comes of patients undergoing ULMCAD PCI.METHODS From January 2004 to December 2015,there were 3,960 patients undergoing ULMCAD PCI at our institution,in-cluding 3,121(78.8%)men and 839(21.2%)women.The clinical outcome included the incidence of major adverse cardiac events(MACE)(the composite of all-cause death,myocardial infarction(MI),and revascularization),all-cause death,MI,revasculariza-tion at three years follow-up.RESULTS Compared with men,women had not significantly different MACE(14.7%vs.14.6%,P = 0.89,all-cause death(3.5%vs.3.7%,P= 0.76),MI(5.0%vs.4.3%,P= 0.38),revascularization(9.1%vs.8.9%,P= 0.86),respectively.After adjustment,rates of MACE(HR = 1.49;95%CI:1.24-1.81;P<0.0001)and all-cause death(HR = 1.65;95%Cl:1.09-2.48;P= 0.017)occurred more fre-quently in male patients,as well as revascularization(HR = 1.46;95%CI:1.16-1.85;P= 0.001).CONCLUSION In this analysis,compared to men,women undergoing ULMCAD PCI have better outcomes of MACE,all-cause death,and revascularization.
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