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目的:探讨新型冠状病毒肺炎（简称新冠肺炎）疫情期间社区疫情防控工作者（简称社区防疫工作者）抑郁焦虑状态及相关因素，为对其进行社会支持和制定心理干预措施提供依据。方法:采用自制问卷在新冠肺炎疫情暴发期对湖南省社区防疫工作者（167?名）以及社区居民（357?名）进行调查，问卷内容包括自编一般情况调查表、新冠肺炎疫情相关调查表、患者健康问卷抑郁症状群量表（Patient Health Questionnare，PHQ-9）、广泛性焦虑量表（Generalized Anxiety Disorder Scale，GAD-7）以及心理弹性量表（Connor-Davidson Resilience Scale，CD-RISC-10），此外采用新冠肺炎防疫工作相关认知调查表对社区防疫工作者的防疫工作认知情况进行调查。采用Mann-Whitney n U检验比较2组抑郁焦虑程度，采用有交互作用的双因素方差分析探究防疫工作和新冠肺炎相关接触史对抑郁焦虑的影响。通过多元线性回归分析探究社区防疫工作者抑郁焦虑情绪的影响因子。n 结果:新冠肺炎疫情期间社区防疫工作者抑郁焦虑评分均高于社区居民（PHQ-9:n Z=2.340，n P=0.019；GAD-7:n Z=4.959，n P<0.01）。社区防疫工作与接触史对抑郁焦虑评分存在显著交互作用（PHQ-9:n F=4.596，n P=0.033；GAD-7:n F=6.566，n P=0.011）。多元线性回归分析表明，心理弹性、社交回避、工作负荷对社区防疫工作者抑郁情绪的解释度为43.1%（n R2=0.431），心理弹性、防护认知、感染风险以及工作负荷对社区防疫工作者焦虑情绪的解释度为41.0%（n R2=0.410）。n 结论:新冠肺炎疫情期间社区防疫工作者抑郁焦虑情绪显著高于社区居民，这种差异由有接触史的社区防控工作者主导。较差的心理弹性和对防疫工作的负性认知可能是引起社区防疫工作者抑郁焦虑情绪的因素。针对这些抑郁焦虑情绪影响因素，应在多个层次上有针对性地为社区防疫工作者提供社会支持和心理支持。“,”Objectives:This study aims to investigate the depression, anxiety, and their predictors in community workers joining the prevention and control work of COVID-19 outbreak.Methods:One-hundred and sixty-seven front-line community workers and 357 community residents completed a set of self-reported questionnaires, including demographics and COVID-19 related questionnaire, Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7) and Connor-Davidson Resilience Scale (CD-RISC-10). Besides, community workers were asked to complete questionnaires about their attitudes towards the COVID-19 prevention and control work. Mann-Whitney n U tests were applied to compare the differences in depression and anxiety between community workers and residents. Two-way ANOVA with interaction was conducted to examine the prevention and control work, the contact history, and their interactive effect on depression and anxiety levels. Multiple linear regression analysis was used to explore the predictors of depression and anxiety.n Results:The anxiety score of community workers was significantly higher than community resident controls, and so did the depression score (PHQ-9:n Z=2.340，n P=0.019；GAD-7:n Z=4.959，n P<0.01). There was a significant interactive effect between COVID-19 prevention and control work with the contact history on depression and anxiety (PHQ-9:n F=4.596, n P=0.033; GAD-7:n F=6.566, n P=0.011). Results of multiple linear regression analysis showed that the score of CD-RISC-10, social avoidance, and workload accounted for 43.1% of the variance in depression (n R2=0.431). Whereas the score of CD-RISC-10, negative appraisals about protection, fear of infection during work, and workload accounted for 41.0% (n R2=0.410) of the variance in anxiety in community workers.n Conclusion:Depression and anxiety among the community workers are significantly higher than that of community controls. The differences between the two groups were mainly driven by community workers who had contact history with patients with confirmed infection. Poorer resilience and negative appraisals of the community work could explain depression and anxiety levels in community workers. Social support and mental health support to address these factors should be reinforced to reduce the depression and anxiety levels in the community workers.