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伴随抗癌基因的发现及研究的深入,又发现一类与抑制肿瘤细胞转移表型相关的基因,这类基因被命名为转移抑制基因。其发现对于肿瘤转移过程的分子机制研究无疑是令人鼓舞的。本文对近年来发现的两种侵袭和转移抑制基因nm23和TIMP的研究现状进行了介绍。
Along with the discovery of anti-oncogenes and the deepening of research, we also discovered a class of genes that are related to the inhibition of tumor cell metastasis phenotypes. These genes are named metastasis suppressor genes. Its discovery is undoubtedly encouraging for the molecular mechanism of tumor metastasis. In this paper, the recent research status of the two invasion and metastasis suppressor genes nm23 and TIMP were introduced.