患者男性,29岁,维吾尔族,以左食指粗大畸形29年为主诉入院。专科检查,左手食指较其它手指明显粗大,长度正常,食指挠侧有多个结节样隆起,质韧,活动度小,尺侧异形不明显。食指活动有力、自如,感觉正常。X片示:食指第二节指骨处有2×1×2cm骨软骨瘤,住院诊断为左侧食指巨指畸形合并骨软骨瘤。手术切除时,发现皮下挠侧指间固有神经为增粗的条索状,色黄,质韧,包膜完整,组织学检查后诊断为神经纤维脂肪性错构瘤。讨论:巨指畸形是一种罕见的先天性畸形,国内报道较少,巨指畸形主要有2种表现,一种为不对称型表现为皮肤、皮下组织异常增生,神经粗大,骨胳发育正常;另一种为对称型,表现为皮肤皮下组织异常增生,神经粗大,包括骨骼发育异常。巨指畸形合 The patient was male, 29 years old, Uighur, with a gross deformity of the left index finger as the main complaint for 29 years. Specialist examination, the left index finger is significantly thicker than other fingers, normal length, index finger flexor side with multiple nodular uplift, quality and toughness, activity is small, ulnar profile is not obvious. The index finger activity is powerful, comfortable and feels normal. X film showed: 2nd 1×2cm osteochondroma in the second phalanx of the index finger. The hospital diagnosis was a malformation of the left index finger and osteochondroma. During surgical resection, it was found that the intrinsic nerves between the subcutaneous flexural digits were thick cords, yellow, tough, and intact capsules. After histological examination, it was diagnosed as adipose nerve hamartoma. Discussion: Giant finger deformity is a rare congenital malformation, domestic reports are less, there are two major performances of giant finger deformity, one is asymmetric manifestations of skin, subcutaneous tissue abnormal proliferation, thick nerves, normal bone development The other type is symmetric, characterized by abnormal proliferation of subcutaneous tissue in the skin and thick nerves, including abnormal bone development. Giant finger malformation