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70年代以来,药物相互作用的研究已进入立体异构体水平。手性药物对映体的立体选择性药物相互作用的研究不断深入,已引起人们的日益重视。本文概述了这种药物相互作用的机理,并对某些代表性的手性药物立体选择性相互作用予以介绍。
Since the 1970s, the study of drug interactions has entered the stereoisomer level. The research on stereoselective drug interactions of enantiomers of chiral drugs has been deepened and has attracted more and more attention. This article outlines the mechanism of this drug interaction and introduces the stereoselective interactions of some representative chiral drugs.