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目的:探讨FLAIR血管高信号征(fluid-attenuated inversion recovery vascular hyperintensities，FVH)与内分水岭脑梗死(internal watershed infarction，IWI)患者的预后及认知功能障碍的相关性。方法:选择IWI患者106例，根据FVH诊断标准分为FVH(＋)组59例，FVH(－)组47例。收集人口统计学、脑血管病危险因素、影像学等资料，评估患者入院时及出院时临床神经功能，出院90 d时采用改良mRS评分对患者进行短期转归的评估，采用MMSE量表对患者的认知功能进行评定。结果:FVH(＋)组和FVH(－)入院时美国国立卫生研究院卒中量表(NIHSS)评分差异无统计学意义(n P>0.05)；FVH(＋)组[(3.37±2.33)分]出院时NIHSS评分明显低于FVH(－)组[(4.43±2.72)分](n P0.05). The NIHSS score of FVH (+ ) group((3.37±2.33))at discharge was significantly lower than that of the FVH (-) group ((4.43±2.72))(n P<0.05). The rate of neural function improvement and mRS score after discharge 90 days in FVH (+ ) group((42.16±12.20)%, (1.75±1.12)) was significantly higher than that in FVH (-) group((37.58±13.64)%, (2.19±1.38))(bothn P<0.05). The scores of orientation, recall and language ability of MMSE in FVH (+ ) group ((9.26±0.21), (1.66±0.27), (7.69±0.44) respectively)were significantly lower than those of FVH (-) group((9.43±0.36), (1.83±0.34), (7.85±0.28) respectively)(alln P0.05).n Conclusion:FVH has no correlation with the severity of IWI patients when they are admitted to hospital.FVH may be used as an imaging sign for prognosis evaluation of patients with IWI .However, IWI patients with FVH may have more severe cognitive impairment.