血清肿瘤标志物 (TM)指一类可通过血清生化和免疫学方法检测出能区别肿瘤与正常组织的物质。理想的 TM应具有高度特异性和敏感性 ,即只在肿瘤患者中表达。 196 3年 Abelev发现甲胎蛋白、196 5年 Gold等发现癌胚抗原以来 ,1975年 Koler和 Miltein建立单克隆抗体技术后 ,各种针 Serum tumor markers (TM) refer to a class of substances that can detect tumors and normal tissues by serum biochemical and immunological methods. The ideal TM should have a high degree of specificity and sensitivity, that is, it should only be expressed in tumor patients. 196 3 years Abelev discovered alpha-fetoprotein, 196-year-old gold, etc. Since the discovery of carcinoembryonic antigen, in 1975 Koler and Miltein established monoclonal antibody technology, various needles