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目的：为截瘫病人受累肌功能恢复提供实验依据。方法：用３０只Ｗｉｓｔａｒ雌性大鼠行Ｔ９节段脊髓横断，于术后３、７、２０、４０和９０天取比目鱼肌（ＳＯＬ）、趾长伸肌（ＥＤＬ）和跖肌（ＰＬ），进行冰冻切片，琥珀酸脱氢酶（ＳＤＨ）染色。结果：实验组与对照组比较ＳＯＬ、ＥＤＬ和ＰＬ的各型肌纤维ＳＤＨ含量降低并呈同步改变，镜下可见部分肌纤维有的横纹暗带染色变深、变宽、出现竹节样改变和局部染色缺失，这种改变在ＳＯＬ出现早于ＥＤＬ和ＰＬ。结论：脊髓横断引起受累肌纤维ＳＤＨ活性和分布改变
Objective: To provide experimental evidence for the recovery of muscle function in patients with paraplegia. Methods: T9 spinal cord was transected in 30 Wistar female rats. The soleus muscle (SOL), EDL and plantar muscle (PL) were taken at 3, 7, 20, 40 and 90 days after operation. Frozen sections were stained with succinate dehydrogenase (SDH). Results: Compared with control group, the content of SDH in all kinds of muscle fibers of SOL, EDL and PL decreased and changed synchronously in the experimental group and the control group. Some of the muscle fibers in the experimental group showed darkening and widening in the horizontal stripes, Dye loss, this change appears earlier in the SOL EDL and PL. CONCLUSIONS: Spinal cord transection caused changes in SDH activity and distribution in affected muscle fibers