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目的 观察重症急性胆管炎 (ACST)的病人凝血的变化。方法 对 30例ACST的病人的临床资料进行回顾性分析。另选择 30例胆囊结石手术病人作为对照组。结果 ACST组血浆中的内毒素 (LPS)含量增高 ,PT和KPTT延长 ,血小板计数减少均较对照组有非常显著的差异 (P <0 0 1) ,纤维蛋白原显著低于对照组 (P <0 0 1)。ECLT两组均无变化。结论 ACST的病人多有凝血障碍 ,随着病情好转上述结果可恢复正常
Objective To observe the changes of coagulation in patients with severe acute cholangitis (ACST). Methods The clinical data of 30 patients with ACST were retrospectively analyzed. Another 30 cases of cholecystolithiasis patients as a control group. Results The plasma levels of endotoxin (LPS), prolongation of PT and KPTT, and platelet count in ACST group were significantly lower than those in control group (P <0.01) and fibrinogen was significantly lower in control group (P < 0 0 1). There was no change in ECLT between the two groups. Conclusion ACST patients have coagulation disorders, with the improvement of the above results can be returned to normal