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测定了423例各型肝炎、肝炎后肝硬化患者一氧化氮代谢物NO2-／NO3-的值，并与42例正常人作对照，结果肝硬化组NO2-/NO3-值高于对照组及其他各型肝炎组（P＜0．01）。肝硬化NO2-／NO3-的升高与血浆白蛋白（ALB）呈负相关，与腹水量呈正相关，与门脉宽度呈正相关．而与TBA、SB、ALT、AST、凝血酶原活动度等无相关性。提示一氧化氮可能在高动力循环、腹水生成、白蛋白合成方面起重要作用。
The NO2- / NO3- values of 423 patients with hepatitis and cirrhosis after hepatitis were measured and compared with 42 healthy controls. The results showed that NO2- / NO3- values in cirrhosis group were higher than those in control group and Other hepatitis groups (P <0.01). The increase of NO2- / NO3- in liver cirrhosis was negatively correlated with plasma albumin (ALB), positively correlated with the amount of ascites and positively correlated with portal vein width. But not with TBA, SB, ALT, AST, prothrombin activity and so on. It is suggested that nitric oxide may play an important role in hyperdynamic circulation, ascites formation and albumin synthesis.