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目的:分析超声引导下硬化剂聚桂醇治疗肝囊肿的临床效果。方法:选择2011年4月~2015年1月我院收治的80例肝囊肿患者作为研究对象,分为对照组、治疗组:对照组36例,接受无水乙醇硬化剂治疗;治疗组44例,接受聚桂醇硬化疗法。测定术前、术后1周、术后6个月两组胆碱酯酶(CHE,cholinesterase)、碱性磷酸酶(ALP,alkaline phosphatase)、天门冬氨酸氨基转移酶(AST,Aspartate aminotransferase)、谷氨酸转氨酶(ALT,Alanine aminotransferas)、总胆红素(TBil,total bilirubin)指标的变化,比较两组治疗效果、治疗不良反应、并发症发生情况、各组住院时间和囊肿闭合时间。结果:(1)术后1周、术后1个月,B组治疗总有效率均高于A组,但仅术后1周总有效率对比差异有统计学意义(P<0.05),两组术后6个月总有效率相近(P>0.05);(2)术后1周,A组ALT、AST上升,与B组对比差异有统计学意义(P<0.05),术后6个月,两组ALT均降低,但对比差异无统计学意义(P>0.05);(3)B组腹痛、囊内出血、醉酒样反应、针道出血发生率均低于A组,但仅腹痛、醉酒样反应发生率对比差异有统计学意义(P<0.05);(4)B组住院时间、囊肿闭合时间均短于A组(P<0.05)。结论:超声引导下聚桂醇硬化疗法治疗肝囊肿,有效率高,对患者肝功能影响小,患者术后恢复速度快,囊肿闭合时间短,安全性高。
OBJECTIVE: To analyze the clinical effect of ultrasound-guided curing agent lauromacyl alcohol in the treatment of hepatic cysts. Methods: From April 2011 to January 2015, 80 patients with hepatic cyst admitted in our hospital were divided into control group, 36 cases in control group, and received anhydrous ethanol sclerotherapy. In treatment group, 44 cases , Receiving lauryl alcohol sclerotherapy. The levels of cholinesterase (CHE), alkaline phosphatase (ALP), aspartate aminotransferase (AST) in the two groups were measured before operation, 1 week after operation and 6 months after operation. , ALT (Alanine aminotransferas) and total bilirubin (TBIL) were compared between the two groups. The treatment effects, adverse reactions, complications, length of stay in each group and time of cyst closure were compared. Results: (1) The total effective rate of group B was significantly higher than that of group A at 1 week and 1 month after operation, but the difference was statistically significant only at 1 week after operation (P <0.05) (P> 0.05). (1) After 1 week, ALT and AST in group A increased significantly compared with group B (P <0.05), and after 6 months (P> 0.05); (3) The incidence of abdominal pain, intracapsular hemorrhage, drunken reaction and needle tract bleeding in group B were lower than those in group A, but only abdominal pain, There were significant differences in the incidence of drunk-like reactions between the two groups (P <0.05). (4) The length of hospital stay and the closure time of cysts in group B were shorter than those in group A (P <0.05). Conclusion: Ultrasound-guided lauromacyl alcohol sclerotherapy is effective in treating hepatic cysts. It has a small effect on the liver function of patients. The recovery rate of the patients is fast, the closure time of the cysts is short, and the safety is high.