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目的探析奥美拉唑、奥曲肽单独与联合应用对非静脉曲张性上消化道出血效果。方法选择我院2011年1月至2014年12月治疗的150例非静脉曲张性上消化道出血患者,随机分为三组,分别给予奥美拉唑、奥曲肽以及奥美拉唑+奥曲肽进行治疗,对比三组患者的临床疗效。结果 C组患者的治疗有效率是94%,A组是86%,B组是64%,差异性显著(P<0.05)。C组患者的出血时间是(16.74±5.57)h,A组是(25.42±4.23)h,B组是(24.84±5.41)h,差异性显著(P<0.05)。C组患者的胃液PH值改善最为显著,明显优于A组、B组,差异性显著(P<0.05)。结论奥美拉唑、奥曲肽的联合用药在非静脉曲张性上消化道出血临床治疗中的效果较为显著,改善患者临床症状。
Objective To investigate the effect of omeprazole and octreotide alone and in combination on non-variceal upper gastrointestinal bleeding. Methods A total of 150 patients with non-variceal upper gastrointestinal bleeding who were treated in our hospital from January 2011 to December 2014 were randomly divided into three groups, which were treated with omeprazole, octreotide and omeprazole + octreotide respectively , Comparing the clinical efficacy of three groups of patients. Results The effective rate of treatment in group C was 94%, in group A 86%, in group B 64%, with significant difference (P <0.05). The bleeding time in group C was (16.74 ± 5.57) h, in group A was (25.42 ± 4.23) h, in group B was (24.84 ± 5.41) h, the difference was significant (P <0.05). The pH value of gastric juice in group C was the most significant improvement, which was significantly better than that in group A and group B (P <0.05). Conclusion The combination of omeprazole and octreotide is effective in the clinical treatment of non-variceal upper gastrointestinal bleeding and improves the clinical symptoms.