论文部分内容阅读
溶脲脲原体感染可引起男性不育。接种溶脲脲原体的正常成年SD雄大鼠与雌大鼠交配,雌鼠的妊娠率与产仔率与相比都有显著差异,提示SD雄大鼠可用于复制溶脲脲原体引起的男性不育动物模型。对人工感染后3个月的雄性大鼠,连续14d每日灌胃给予美满霉素20mg/kg,在停药后8周,感染组雄性大鼠恢复生育力。
Infection with Ureaplasma urealyticum can cause male infertility. Normal adult SD rats inoculated with Ureaplasma urealyticum had significant differences in pregnancy rate and litter size compared with female rats, suggesting that SD male rats can be used to replicate the male Infertility animal model. Male rats 3 months after artificial infection were treated with 20 mg / kg of minocycline by intragastric administration for 14 days. After 8 weeks, the male rats in the infected group were restored fertility.