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目的:探讨氯吡格雷和前列地尔联用治疗不稳定型心绞痛的疗效及安全性。方法:常规组30例给予基本抗心绞痛治疗;治疗组30例在以上治疗基础上加用硫酸氯吡格雷和前列地尔治疗后分别观察心绞痛症状、心电图变化及不良反应等。结果:氯吡格雷联合前列地尔治疗不稳定型心绞痛的患者心绞痛症状缓解率及心电图改善率分别为96.67%和83.33%,且无明显不良反应。结论:氯吡格雷和前列地尔联合应用可以显著提高治疗不稳定型心绞痛的疗效,而且不良反应小,值得临床广泛应用。
Objective: To investigate the efficacy and safety of clopidogrel combined with prostaglandin in the treatment of unstable angina pectoris. Methods: Thirty patients in the conventional group were treated with basic anti-angina pectoris. In the treatment group, 30 cases were treated with clopidogrel sulfate and alprostadil for 30 cases. Angina pectoris, electrocardiogram changes and adverse reactions were observed respectively. Results: The rates of improvement of angina pectoris and ECG were 96.67% and 83.33% in patients with unstable angina pectoris treated with clopidogrel and alprostadil, respectively. There was no obvious adverse reaction. Conclusion: The combination of clopidogrel and alprostadil can significantly improve the efficacy of treatment of unstable angina pectoris, and the adverse reaction is small, it is widely used in clinical.