论文部分内容阅读
目的:探讨磷霉素钙在治疗幽门螺杆菌相关性消化性溃疡的临床效果。方法:选择胃镜确诊的80例幽门螺杆菌阳性消化道溃疡患者,随机分为治疗组和对照组各40例,治疗组给予磷霉素钙0.8g,3次/日,甲硝唑0.4g,3次/日,奥美拉唑20mg,2次/日;对照组给予阿莫西林1.0g,3次/日,甲硝唑0.4g,3次/日,奥美拉唑20mg,2次/日;疗程均为14天。停药4周胃镜复查。结果:治疗组有效率95%,对照组有效率96%。两组疗效无统计学差异(P>0.05)。结论:磷霉素钙三联疗法治疗幽门螺杆菌阳性消化性溃疡效果良好,无过敏反应,不需要皮试。
Objective: To investigate the clinical effect of fosfomycin calcium in the treatment of Helicobacter pylori-associated peptic ulcer. Methods: Eighty patients with Helicobacter pylori-positive peptic ulcer diagnosed by gastroscopy were randomly divided into treatment group (40 cases) and control group (40 cases). The patients in treatment group were given fosfomycin calcium 0.8g, 3 times daily, metronidazole 0.4g, Omeprazole 20mg, twice a day; control group was given amoxicillin 1.0g, 3 times / day, metronidazole 0.4g, 3 times / day, omeprazole 20mg, 2 times / Day; treatment are 14 days. Discontinued 4 weeks gastroscopy review. Results: The effective rate was 95% in the treatment group and 96% in the control group. No significant difference between the two groups (P> 0.05). Conclusion: Fosfomycin calcium triple therapy for Helicobacter pylori positive peptic ulcer with good results, no allergic reactions, no skin test.